small-daily-dose

 A small, daily dose of Viagra may reduce colorectal cancer risk – an article by ScienceDaily can be accessed here.

Comments from Dr. Rosenberg on the Article:

Over the last decade, researchers have elucidated the roles that impairment of cGMP signaling pathway by PDE5 activity inhibition plays in the regulation of tumor development, and progression.

PDE5 inhibition could be associated with a decreased risk of human cancer development and suppression of tumor progression in several malignancies including those of the lung, prostate, breast and colon. PDE5 inhibitors may also provide an additional anti-tumor immune response in patients affected by myeloma and head and neck squamous cell carcinomas. In addition, a synergistic effect with current chemotherapeutic regimens and monoclonal antibodies has been reported.

Although it likely will not cause harm to use PDE5 inhibitors as both a cancer preventative, as well as an adjunct to existing therapies, some questions need to be answered:

1. Which are the most effective class of PDE5 inhibitors against cancer?

2. Within each class, which drug(s) is the most effective?

3. Optimal dosage?

December 20th, 2018

Posted In: cancer care, Cancer Prevention, Healthy Lifestyle

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